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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRM3
All Species:
17.88
Human Site:
T506
Identified Species:
32.78
UniProt:
Q14832
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14832
NP_000831.2
879
98879
T506
W
S
R
N
S
V
P
T
S
Q
C
S
D
P
C
Chimpanzee
Pan troglodytes
A3QNZ8
839
95029
K497
I
P
V
S
M
C
S
K
R
C
Q
S
G
Q
K
Rhesus Macaque
Macaca mulatta
XP_001107588
879
98905
T506
W
S
R
N
S
V
P
T
S
Q
C
S
D
P
C
Dog
Lupus familis
XP_541867
872
95696
S494
W
A
S
P
S
A
S
S
L
P
A
S
R
C
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9QYS2
879
99096
T506
W
S
R
N
S
V
P
T
S
Q
C
S
D
P
C
Rat
Rattus norvegicus
P31422
879
98942
T506
W
S
R
N
S
V
P
T
S
Q
C
S
D
P
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515487
775
87278
Y435
I
P
C
E
P
Y
E
Y
L
A
D
E
F
T
C
Chicken
Gallus gallus
XP_416842
879
98936
V506
W
S
K
S
S
V
P
V
S
Q
C
S
D
P
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5U9X3
867
97118
Y503
N
S
C
Q
P
G
Q
Y
K
K
T
A
E
G
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91685
976
108467
G534
G
Y
Q
Y
K
V
I
G
K
W
F
N
G
L
Q
Honey Bee
Apis mellifera
NP_001011624
933
103448
I536
R
G
T
K
D
I
P
I
S
A
C
S
L
P
C
Nematode Worm
Caenorhab. elegans
Q09630
999
113258
T572
M
D
K
K
R
R
M
T
D
D
E
S
S
P
S
Sea Urchin
Strong. purpuratus
XP_784936
1474
165598
N1077
L
G
D
Y
N
S
H
N
V
P
Y
S
Q
C
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
25.9
99.5
68.7
N.A.
96.6
96.5
N.A.
79.1
91
N.A.
26.5
N.A.
46
48.2
39.4
33.3
Protein Similarity:
100
45.3
99.6
82.3
N.A.
98.7
98.5
N.A.
83.8
95.4
N.A.
46
N.A.
61.6
64.7
57.1
44.9
P-Site Identity:
100
6.6
100
20
N.A.
100
100
N.A.
6.6
80
N.A.
6.6
N.A.
6.6
40
20
6.6
P-Site Similarity:
100
13.3
100
33.3
N.A.
100
100
N.A.
6.6
93.3
N.A.
26.6
N.A.
20
46.6
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
8
0
0
0
16
8
8
0
0
0
% A
% Cys:
0
0
16
0
0
8
0
0
0
8
47
0
0
16
54
% C
% Asp:
0
8
8
0
8
0
0
0
8
8
8
0
39
0
0
% D
% Glu:
0
0
0
8
0
0
8
0
0
0
8
8
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% F
% Gly:
8
16
0
0
0
8
0
8
0
0
0
0
16
8
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
16
0
0
0
0
8
8
8
0
0
0
0
0
0
0
% I
% Lys:
0
0
16
16
8
0
0
8
16
8
0
0
0
0
8
% K
% Leu:
8
0
0
0
0
0
0
0
16
0
0
0
8
8
0
% L
% Met:
8
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
31
8
0
0
8
0
0
0
8
0
0
0
% N
% Pro:
0
16
0
8
16
0
47
0
0
16
0
0
0
54
0
% P
% Gln:
0
0
8
8
0
0
8
0
0
39
8
0
8
8
16
% Q
% Arg:
8
0
31
0
8
8
0
0
8
0
0
0
8
0
0
% R
% Ser:
0
47
8
16
47
8
16
8
47
0
0
77
8
0
24
% S
% Thr:
0
0
8
0
0
0
0
39
0
0
8
0
0
8
0
% T
% Val:
0
0
8
0
0
47
0
8
8
0
0
0
0
0
0
% V
% Trp:
47
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
8
0
16
0
8
0
16
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _